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1

Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor κB decoy oligodeoxynucleotides as a gene therapy

Tetsuya Tomita, Eiji Takeuchi, Naruya Tomita, Ryuichi Morishita, Motoharu Kaneko, Kei Yamamoto, Takanobu Nakase, Hiroshi Seki, Kazuyo Kato, Yasufumi Kaneda, Takahiro Ochi

Journal:

Arthritis & Rheumatism

Year:

1999

Language:

english

File:

PDF, 381 KB

english, 1999

2

In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes

Tetsuya Tomita, Hideo Hashimoto, Naruya Tomita, Ryuichi Morishita, Seung Bak Lee, Kenji Hayashida, Norimasa Nakamura, Kazuo Yonenobu, Yasufumi Kaneda, Takahiro Ochi

Journal:

Arthritis & Rheumatism

Year:

1997

Language:

english

File:

PDF, 695 KB

english, 1997

3

EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy

Takanobu Otomo, Seiji Yamamoto, Ryuichi Morishita, Yasufumi Kaneda

Journal:

The Journal of Gene Medicine

Year:

2001

Language:

english

File:

PDF, 361 KB

english, 2001

4

Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes

Naruya Tomita, Ryuichi Morishita, Kei Yamamoto, Jitsuo Higaki, Victor J. Dzau, Toshio Ogihara, Yasufumi Kaneda

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 615 KB

english, 2002

5

Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles

Munehisa Shimamura, Naoyuki Sato, Yoshiaki Taniyama, Hitomi Kurinami, Hiroyuki Tanaka, Toshihiro Takami, Toshio Ogihara, Masaya Tohyama, Yasufumi Kaneda, Ryuichi Morishita

Journal:

The Journal of Gene Medicine

Year:

2005

Language:

english

File:

PDF, 754 KB

english, 2005

6

Novel laser system and laser irradiation method reduced the risk of carbonization during laser interstitial thermotherapy: Assessed by MR temperature measurement

Hideki Atsumi, Mitsunori Matsumae, Michihiro Kaneda, Isao Muro, Yoshiaki Mamata, Taizo Komiya, Atsushi Tsugu, Ryuichi Tsugane

Journal:

Lasers in Surgery and Medicine

Year:

2001

Language:

english

File:

PDF, 1.40 MB

english, 2001

7

Identification of face-to-face inclusion complex formation of cyclodextrin bearing an azobenzene group by electrospray ionization mass spectrometry

Ryuichi Arakawa, Takahiro Yamaguchi, Atsushi Takahashi, Tatsuhiko Fujimoto, Takahiro Kaneda

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

8

Efficient gene transfer from innervated muscle into rat peripheral and central nervous systems using a non-viral haemagglutinating virus of Japan (HVJ)-liposome method

Naoki Kato, Kuniaki Nakanishi, Koichi Nemoto, Ryuichi Morishita, Yasufumi Kaneda, Maki Uenoyama, Tomosumi Ikeda, Kyosuke Fujikawa

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

9

Prevention of Restenosis by Gene Therapy

YASUFUMI KANEDA, RYUICHI MORISHITA, VICTOR J. DZAU

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 623 KB

english, 1997

10

Gene Therapy for Heart Transplantation-Associated Coronary Arteriosclerosis

MITSUAKI ISOBE, JUN-ICHI SUZUKI, RYUICHI MORISHITA, YASUFUMI KANEDA, JUN AMANO

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 471 KB

english, 2000

11

Gene Therapy for Cardiovascular Disease Using Hepatocyte Growth Factor

RYUICHI MORISHITA, MOTOKUNI AOKI, SHIGEFUMI NAKAMURA, JITSUO HIGAKI, YASUFUMI KANEDA, TOSHIO OGIHARA

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 77 KB

english, 2000

12

Decoy Oligodeoxynucleotides As Novel Cardiovascular Drugs for Cardiovascular Disease

RYUICHI MORISHITA, MOTOKUNI AOKI, YASUFUMI KANEDA

Journal:

Annals of the New York Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 1.50 MB

english, 2001

13

10.1038/5593

Fujimoto, Jiro, Ueki, Takahiro, Kaneda, Yasufumi, Tsutsui, Hiroko, Nakanishi, Kenji, Sawa, Yoshiki, Morishita, Ryuichi, Matsumoto, Kunio, Nakamura, Toshikazu, Takahashi, Hiroshi, Okamoto, Eizo

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

14

Prevention of graft coronary arteriosclerosis by antisense cdk2 kinase oligonucleotide

Suzuki, Jun-Ichi, Isobe, Mitsuaki, Morishita, Ryuichi, Aoki, Motokuni, Horie, Shiro, Okubo, Yoshio, Kaneda, Yasufumi, Sawa, Yoshiki, Matsuda, Hikaru, Ogihara, Toshio

Journal:

Nature Medicine

Year:

1997

File:

PDF, 419 KB

1997

15

In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction

Morishita, Ryuichi, Sugimoto, Toshiko, Aoki, Motokuni, Kida, Iwao, Tomita, Naruya, Moriguchi, Atsushi, Maeda, Kazuhiro, Sawa, Yoshiki, Kaneda, Yasufumi, Higaki, Jitsuo

Journal:

Nature Medicine

Year:

1997

File:

PDF, 739 KB

1997

16

Novel immunotherapy for peritoneal dissemination of murine colon cancer with macrophage inflammatory protein-1β mediated by a tumor-specific vector, HVJ cationic liposomes

Miyata, Toshio, Yamamoto, Seiji, Sakamoto, Kayo, Morishita, Ryuichi, Kaneda, Yasufumi

Journal:

Cancer Gene Therapy

Year:

2001

Language:

english

File:

PDF, 2.58 MB

english, 2001

17

A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma

Yamamoto, Seiji, Yamano, Tomoki, Tanaka, Maki, Hoon, Dave S B, Takao, Sonshin, Morishita, Ryuichi, Aikou, Takashi, Kaneda, Yasufumi

Journal:

Cancer Gene Therapy

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

18

Nuclear factor κB decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model

Ichiro Ogushi, Yuji Iimuro, Ekihiro Seki, Gakuhei Son, Tadamichi Hirano, Toshikazu Hada, Hiroko Tsutsui, Kenji Nakanishi, Ryuichi Morishita, Yasufumi Kaneda, Jiro Fujimoto

Journal:

Year:

2003

Language:

english

File:

PDF, 503 KB

english, 2003

19

Gene therapy in vascular medicine: recent advances and future perspectives

Ryuichi Morishita, Motokuni Aoki, Yasufumi Kaneda, Toshio Ogihara

Journal:

Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

20

Gene therapy using HVJ-liposomes: the best of both worlds?

Yasufumi Kaneda, Yoshinaga Saeki, Ryuichi Morishita

Journal:

Molecular Medicine Today

Year:

1999

Language:

english

File:

PDF, 369 KB

english, 1999

21

Nuclear factor-κB decoy attenuates neuronal damage after global brain ischemia: A future strategy for brain protection during circulatory arrest

Takayoshi Ueno, Yoshiki Sawa, Satoru Kitagawa-Sakakida, Motonobu Nishimura, Ryuichi Morishita, Yasufumi Kaneda, Eiji Kohmura, Toshiki Yoshimine, Hikaru Matsuda

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

22

Autocrine–Paracrine Effects of Overexpression of Hepatocyte Growth Factor Gene on Growth of Endothelial Cells

Shin-ichiro Hayashi, Ryuichi Morishita, Jitsuo Higaki, Motokuni Aoki, Atushi Moriguchi, Iwao Kida, Sawa Yoshiki, Kunio Matsumoto, Toshikazu Nakamura, Yasufumi Kaneda, Toshio Ogihara

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 88 KB

english, 1996

23

Sustained Transgene Expression by Transfection of Renin Gene into Liver of Neonates

Naruya Tomita, Ryuichi Morishita, Jitsuo Higaki, Sawako Tomita, Motokuni Aoki, Yasufumi Kaneda, Toshio Ogihara

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 593 KB

english, 1996

24

In VivoTransfer Efficiency of Antisense Oligonucleotides into the Myocardium Using HVJ–Liposome Method

Motokuni Aoki, Ryuichi Morishita, Jitsuo Higaki, Atsushi Moriguchi, Iwao Kida, Shin-ichiro Hayashi, Hidetsugu Matsushita, Yasufumi Kaneda, Toshio Ogihara

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 372 KB

english, 1997

25

Role of AP-1 Complex in Angiotensin II-Mediated Transforming Growth Factor-β Expression and Growth of Smooth Muscle Cells: Using Decoy Approach against AP-1 Binding Site

Ryuichi Morishita, Gary H. Gibbons, Masatsugu Horiuchi, Yasufumi Kaneda, Toshio Ogihara, Victor J. Dzau

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 325 KB

english, 1998

26

Stimulatory Effect of Lipoprotein (a) on Proliferation of Human Mesangial Cells: Role of Lipoprotein (a) in Renal Disease

Ryuichi Morishita, Kei Yamamoto, Shingo Yamada, Hidetsugu Matsushita, Naruya Tomita, Ikunosuke Sakurabayashi, Yasufumi Kaneda, Atsushi Moriguchi, Jitsuo Higaki, Toshio Ogihara

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

27

Systemic Administration of HVJ Viral Coat–Liposome Complex Containing Human Insulin Vector Decreases Glucose Level in Diabetic Mouse: A Model of Gene Therapy

Ryuichi Morishita, Gary H. Gibbons, Yasufumi Kaneda, Toshio Ogihara, Victor J. Dzau

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 184 KB

english, 2000

28

Fusigenic Liposome-mediated DNA Transfer into Cardiac Myocytes

Kristin E. Ellison, Nanette H. Bishopric, Keith A. Webster, Ryuichi Morishita, Gary H. Gibbons, Yasufumi Kaneda, Barbara Sato, Victor J. Dzau

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1996

Language:

english

File:

PDF, 4.52 MB

english, 1996

29

EfficientIn VivoGene Transfer into the Heart in the Rat Myocardial Infarction Model Using the HVJ (Hemagglutinating Virus of Japan)—Liposome Method

Motokuni Aoki, Ryuichi Morishita, Akihiko Muraishi, Atsushi Moriguchi, Toshiko Sugimoto, Kazuhiro Maeda, Victor J. Dzau, Yasufumi Kaneda, Jitsuo Higaki, Toshio Ogihara

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1997

Language:

english

File:

PDF, 3.42 MB

english, 1997

30

Determination of gaseous and particulate chloride and fluoride in the atmosphere

Toshiichi Okita, Kazuko Kaneda, Takaaki Yanaka, Ryuichi Sugai

Journal:

Atmospheric Environment (1967)

Year:

1967

Language:

english

File:

PDF, 710 KB

english, 1967

31

No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice

Atsushi Matsuki, Seiji Yamamoto, Hironori Nakagami, Motokuni Aoki, Katsuto Tamai, Kunio Matsumoto, Toshikazu Nakamura, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 383 KB

english, 2004

32

Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model

Naotaka Hashiya, Motokuni Aoki, Katsuro Tachibana, Yoshiaki Taniyama, Keita Yamasaki, Kazuya Hiraoka, Hirofumi Makino, Kaneda Yasufumi, Toshio Ogihara, Ryuichi Morishita

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 360 KB

english, 2004

33

Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector

Norio Morishita, Hironori Nakagami, Ryuichi Morishita, Shin-ichi Takeda, Fumihito Mishima, BungoTerazono, Shigehiro Nishijima, Yasufumi Kaneda, Noriaki Tanaka

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 1.54 MB

english, 2005

34

The effect of VEGF on blood vessels and blood cells during Xenopus development

Nobutaka Koibuchi, Yoshiaki Taniyama, Kaori Nagao, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 1.60 MB

english, 2006

35

Involvement of γ-secretase in postnatal angiogenesis

Hiroki Hayashi, Hironori Nakagami, Yoichi Takami, Naoyuki Sato, Yukihiro Saito, Tomoyuki Nishikawa, Masaki Mori, Hiroshi Koriyama, Katsuto Tamai, Ryuichi Morishita, Yasufumi Kaneda

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 365 KB

english, 2007

36

Molecular therapy to inhibit NFκB activation by transcription factor decoy oligonucleotides

Ryuichi Morishita, Naruya Tomita, Yasufumi Kaneda, Toshio Ogihara

Journal:

Current Opinion in Pharmacology

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

37

Modification of plasmid DNA-based gene transfer into central nerve system

Yoshiaki Taniyama, Munehisa Shimamura, Naoyuki Sato, Naruya Tomita, Masayuki Endho, Junya Azuma, Kazuma Iekushi, Yasufumi Kaneda, Toshio Ogihara, Ryuichi Morishita

Journal:

International Congress Series

Year:

2004

Language:

english

File:

PDF, 76 KB

english, 2004

38

Nonviral HVJ (hemagglutinating virus of Japan) liposome-mediated retrograde gene transfer of human hepatocyte growth factor into rat nervous system promotes functional and histological recovery of the crushed nerve

Naoki Kato, Koichi Nemoto, Kuniaki Nakanishi, Ryuichi Morishita, Yasufumi Kaneda, Maki Uenoyama, Tomosumi Ikeda, Kyosuke Fujikawa

Journal:

Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 629 KB

english, 2005

39

Development of novel method of non-viral efficient gene transfer into neonatal cardiac myocytes

Hironori Tashiro, Motokuni Aoki, Mitsuaki Isobe, Naotaka Hashiya, Hirofumi Makino, Yasufumi Kaneda, Toshio Ogihara, Ryuichi Morishita

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2005

Language:

english

File:

PDF, 3.70 MB

english, 2005

40

Inhibitory effects of NFκB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model

Takashi Miyake, Motokuni Aoki, Suguru Shiraya, Kazuo Tanemoto, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 514 KB

english, 2006

41

Cold shock domain protein A, novel endogenous regulator of angiogenesis in heart

Yukihiro Saito, Hironori Nakagami, Nobuyoshi Azuma, Ryuichi Morishita, Yasufumi Kaneda, Tadahiro Sasajima

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

42

Gene Transfer of Human Hepatocyte Growth Factor into Rat Skin Wounds Mediated by Liposomes Coated with the Sendai Virus (Hemagglutinating Virus of Japan)

Kuniaki Nakanishi, Maki Uenoyama, Naruya Tomita, Ryuichi Morishita, Yasufumi Kaneda, Toshio Ogihara, Kunio Matsumoto, Toshikazu Nakamura, Akie Maruta, Shigeo Matsuyama, Toshiaki Kawai, Takashi Aurues,

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 1.66 MB

english, 2002

43

Gene transfer to vein graft wall by HVJ–liposome method: time course and localization of gene expression

Hong-zhi Bai, Yoshiki Sawa, Wei-da Zhang, Tomoyuki Yamakawa, Ryuichi Morishita, Yasufumi Kaneda, Hikaru Matsuda

Journal:

The Annals of Thoracic Surgery

Year:

1998

Language:

english

File:

PDF, 706 KB

english, 1998

44

HVJ-envelope vector for gene transfer into central nervous system

Munehisa Shimamura, Ryuichi Morishita, Masayuki Endoh, Kazuo Oshima, Motokuni Aoki, Satoshi Waguri, Yasuo Uchiyama, Yasufumi Kaneda

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 292 KB

english, 2003

45

Direct in vivo gene introduction into rat kidney

Naruya Tomita, Jitsuo Higaki, Ryuichi Morishita, Keiko Kato, Hiroshi Mikami, Yasufumi Kaneda, Toshio Ogihara

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 2.12 MB

english, 1992

46

Egr-1 in vascular smooth muscle cell proliferation in response to allo-antigen

Yuko Wada, Minoru Fujimori, Jun-ichi Suzuki, Katsuaki Tsukioka, Ken-ichi Ito, Yoshiki Sawa, Ryuichi Morishita, Yasufumi Kaneda, Mitsuaki Isobe, Jun Amano

Journal:

Journal of Surgical Research

Year:

2003

Language:

english

File:

PDF, 542 KB

english, 2003

47

N141I mutant Presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression

Masaki Mori, Hironori Nakagami, Ryuichi Morishita, Noriaki Mitsuda, Kei Yamamoto, Shin-ichi Yoshimura, Nobutaka Ohkubo, Naoyuki Sato, Toshio Ogihara, Yasufumi Kaneda

Journal:

Year:

2002

Language:

english

File:

PDF, 284 KB

english, 2002

48

Potential Role of CYLD (Cylindromatosis) as a Deubiquitinating Enzyme in Vascular Cells

Yoichi Takami, Hironori Nakagami, Ryuichi Morishita, Tomohiro Katsuya, Hiroki Hayashi, Masaki Mori, Hiroshi Koriyama, Yoshichika Baba, Osamu Yasuda, Hiromi Rakugi, Toshio Ogihara, Yasufumi Kaneda

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 2.18 MB

english, 2008

49

Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway

Rodriguez-Araujo, Gerardo, Nakagami, Hironori, Hayashi, Hiroki, Mori, Masaki, Shiuchi, Tetsuya, Minokoshi, Yasuhiko, Nakaoka, Yoshikazu, Takami, Yoichi, Komuro, Issei, Morishita, Ryuichi, Kaneda, Yasu

Journal:

Cellular and Molecular Life Sciences

Year:

2013

Language:

english

File:

PDF, 635 KB

english, 2013

50

Intramuscular gene transfer of interleukin-10 cDNA reduces atherosclerosis in apolipoprotein E-knockout mice

Masayuki Namiki, Seinosuke Kawashima, Tomoya Yamashita, Masanori Ozaki, Tsuyoshi Sakoda, Nobutaka Inoue, Ken-Ichi Hirata, Ryuichi Morishita, Yasufumi Kaneda, Mitsuhiro Yokoyama

Journal:

Atherosclerosis

Year:

2004

Language:

english

File:

PDF, 464 KB

english, 2004

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